NEW YORK, Dec. 14, 2018 (GLOBE NEWSWIRE) — Nasdaq (Nasdaq:NDAQ) today announced the results of the annual re-ranking of the NASDAQ Biotechnology Index (Nasdaq:NBI), which will become effective prior to market open on Monday, December 24, 2018.
The following 60 securities will be added to the Index:
| EXCHANGE | SYMBOL | COMPANY NAME |
| Nasdaq | ACIU | Ac Immune SA |
| Nasdaq | ACRX | AcelRx Pharmaceuticals, Inc. |
| Nasdaq | ADVM | Adverum Biotechnologies |
| Nasdaq | AGLE | Aeglea BioTherapeutics, Inc. |
| Nasdaq | AKRX | Akorn Inc. |
| Nasdaq | ALLK | Allakos Inc. |
| Nasdaq | AMRS | Amyris Inc. |
| Nasdaq | APLS | Apellis Pharma Inc. |
| Nasdaq | APTX | Aptinyx Inc. |
| Nasdaq | AQST | Aquestive Therapeutics |
| Nasdaq | ARGX | Argenx Se Ads |
| Nasdaq | ARQL | ArQule Inc. |
| Nasdaq | AUTL | Autolus Therapeutics Ltd. |
| Nasdaq | AVRO | AVROBIO Inc. |
| Nasdaq | CBAY | CymaBay Therapeutics |
| Nasdaq | CRNX | Crinetics Pharmaceuticals |
| Nasdaq | DCPH | Deciphera Pharmaceuticals |
| Nasdaq | DNLI | Denali Therapeutics Inc. |
| Nasdaq | DRNA | Dicerna Pharmaceuticals Inc. |
| Nasdaq | EIDX | Eidos Therapeutics Inc. |
| Nasdaq | EIGR | Eiger BioPharma |
| Nasdaq | ELOX | Eloxx Pharman |
| Nasdaq | EOLS | Evolus Inc. |
| Nasdaq | EYPT | EyePoint Pharma Inc. |
| Nasdaq | FATE | Fate Therapeutics Inc. |
| Nasdaq | FIXX | Homology Medicines Inc. |
| Nasdaq | FTSV | Forty Seven Inc. |
| Nasdaq | HCM | Hutchison China MediTech |
| Nasdaq | KNSA | Kiniksa Pharma Ltd. |
| Nasdaq | MGTA | Magenta Therapeutics |
| Nasdaq | MNOV | Medicinova Inc. |
| Nasdaq | MRTX | Mirati Therapeutics Inc. |
| Nasdaq | OCUL | Ocular Therapeutix Inc. |
| Nasdaq | OPTN | OptiNose Inc. |
| Nasdaq | PRQR | ProQR Therapeutics N.V. |
| Nasdaq | PTI | Proteostasis Therapeutic |
| Nasdaq | QTRX | Quanterix Corporation |
| Nasdaq | RCKT | Rocket Pharmaceuticals |
| Nasdaq | REPL | Replimune Group Inc. |
| Nasdaq | RUBY | Rubius Therapeutics |
| Nasdaq | RYTM | Rhythm Pharmaceuticals |
| Nasdaq | SIGA | SIGA Technologies Inc. |
| Nasdaq | SLDB | Solid Biosciences Inc. |
| Nasdaq | STIM | Neuronetics, Inc. |
| Nasdaq | SURF | Surface Oncology Inc. |
| Nasdaq | SYBX | Synlogic Inc. |
| Nasdaq | SYRS | Syros Pharmaceuticals |
| Nasdaq | TBIO | Translate Bio Inc. |
| Nasdaq | TCDA | Tricida Inc. |
| Nasdaq | TORC | resTORbio Inc. |
| Nasdaq | UBX | Unity Biotechnology |
| Nasdaq | UMRX | Unum Therapeutics Inc. |
| Nasdaq | URGN | UroGen Pharma Ltd. |
| Nasdaq | VSTM | Verastem Inc. |
| Nasdaq | WVE | Wave Life Sciences |
| Nasdaq | XENE | Xenon Pharmaceuticals |
| Nasdaq | XERS | Xeris Pharmaceuticals |
| Nasdaq | XON | Intrexon Corporation |
| Nasdaq | ZFGN | Zafgen Inc. |
| Nasdaq | ZLAB | Zai Lab Ltd. |
The Index is designed to track the performance of a set of securities listed on The Nasdaq Stock Market® (NASDAQ®) that are classified as either biotechnology or pharmaceutical according to the Industry Classification Benchmark (ICB).
As a result of the re-ranking, the following 26 securities will be removed from the Index:
| EXCHANGE | SYMBOL | COMPANY NAME |
| Nasdaq | AKAO | Achaogen Inc. |
| Nasdaq | ARDX | Ardelyx Inc. |
| Nasdaq | AVDL | Avadel Pharmaceuticals PLC |
| Nasdaq | BLCM | Bellicum Pharmaceuticals |
| Nasdaq | CALA | Calithera Biosciences |
| Nasdaq | CLDX | Celldex Therapeutics, Inc. |
| Nasdaq | CLXT | Calyxt, Inc. |
| Nasdaq | CMRX | Chimerix, Inc. |
| Nasdaq | CRIS | Curis Inc. |
| Nasdaq | CRVS | Corvus Pharma |
| Nasdaq | JNCE | Jounce Therapeutics, Inc. |
| Nasdaq | MRNS | Marinus Pharmaceuticals |
| Nasdaq | MRSN | Mersana Therapeutics |
| Nasdaq | NBRV | Nabriva Therapeutics PLC |
| Nasdaq | NEOS | Neos Therapeutics Inc. |
| Nasdaq | NH | NantHealth Inc. |
| Nasdaq | NK | NantKwest Inc. |
| Nasdaq | NLNK | NewLink Genetics Corporation |
| Nasdaq | RGEN | Repligen Corporation |
| Nasdaq | SGYP | Synergy Pharmaceuticals Inc. |
| Nasdaq | SHPG | Shire PLC |
| Nasdaq | SNDX | Syndax Pharmaceuticals |
| Nasdaq | SNNA | Sienna Biopharmaceuticals |
| Nasdaq | TLGT | Teligent Inc. |
| Nasdaq | TTPH | Tetraphase Pharmaceuticals Inc. |
| Nasdaq | VTL | Vital Therapies Inc. |
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